ROAD

Dean drives along the road to a bridge, which is blocked by a roadblock consisting of several cars and a half-dozen locals with guns. One is Jake. He stops the car, frowning. Something bangs down on the roof of the car and he jumps; a man leans over

"Oh-ho-ho. Hey." Dean Says

"Sorry. Road's closed." The Man Says

"Yeah, I can see that. What's up?" Dean Asks

"Quarantine." The Man Says

"Quarantine? What is it?" Dean Asks

"Don't know. Something going around out there." The Man Says

"Uh-huh. Who told you that?"Dean Says

"County Sheriff." The Man Says

"Is he here?"Dean Asks

"No. He called. Say, why don't you get out of the car and we'll talk a little?" The Man Says

"Well, you are a handsome devil, but I don't swing that way, sorry." Dean Says

"I'd sure appreciate it if you got out of the car, just for a quick minute." The Man Says

"Yeah, I'll bet you would." Dean Says As he puts the car into a quick reverse; the man grabs his collar and is dragged along. The men at the roadblock begin firing, and Dean swings the car around, shaking the Man off and zooming away.

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THE CLINIC

Sam is staring intently at Beverly still huddled on the stool in the lab.

"I don't understand. Are you saying my husband and Jake had a disease?" Beverly Asks

"That's what we're trying to find out. Now, during the attack, do you remember . . . did you have any direct contact with their blood?" Dr.Lee Says

"Oh my God. You don't think I've got this virus, do you?" Beverly Asks

"Beverly, I don't know what to think. But with your permission, we'll take a blood sample." Dr.Lee Says
Beverly nods and lays her hand gently on Dr.Lee Suddenly she grabs Dr.Lee's wrist and yells in rage, lashing out with her other hand. Sam advances on her and she tosses him against a glass cabinet, which shatters. She picks up a scalpel as he takes a fire extinguisher from the wall; she advances on him, still yelling. Elena knocks her out.

Dean is driving back into town; Mark steps into his path brandishing a rifle, and he stops the car.

"Hands where I can see 'em!" Mark Says

"Son of a-" Dean Says

"Get out of the car! Out of the car!" Mark Says

He Opens the door slowly, "All right, easy there, big guy." Dean Says As he stands, Dean pulls out a handgun and points it at Mark. All right, put it down!"

"Lower it now!" Mark Says

"Put it down!" Dean Says

"Are you one of 'em?" Mark Asks

"No! Are you?"Dean Asks

"No!" Mark Says

"You could be lying!" Dean Says

"So could you!" Mark Says

"All right! All right. We could do this all day, all right? Let's just uh, let's take it easy before we kill each other." Dean Says

"What's going on with everybody?" Mark Asks

"I don't know." Dean Asks

"My neighbor . . . Mr. Rogers, he —" Mark Says

"You've got a neighbor named Mr. Rogers?" Dean Says

"He came at me with a hatchet. I put him down. He's not the only one, I mean, it's happening to everyone." Mark Says

"I'm heading over to the Doc's place, there's still some people left." Dean Says

"No, no way. I'm getting the hell out." Mark Says

"There's no way out, they got the bridge covered, now come on." Dean Says

"I don't believe you." Mark Says

"Fine, stay here, be my guest." Dean Says As Mark hesitates, then changes his mind. He pulls out a handgun and keeps it pointed towards Dean as he gets into the passenger's side; Dean still has his gun up as well. He mutters,Well, this ought to be a relaxing drive."

__________________________________
THE CLINC

Dr.Lee is again looking through the microscope; Pam huddles against the far wall.

"What if we all have it? What if we all go crazy?" Pam Asks

"You've got to stay calm. All we can do is wait. The Marshal's bringing help." Dr.Lee Says

"I can't, I . . . I've got to go."Pam Says

"Pam!" Dr.Lee Says

"No, you don't understand. My boyfriend's out there, I gotta make sure he's okay." Pam Says As She hurries out of the lab, and Sam follows her all the way to the lobby.

"All right, wait, wait. Please. Look, I know you're upset, all right? But it's safer if you stay here for now. Help is coming." Sam Says As We hear the Impala pull up outside.

"There they are." Elena Says

"Sammy? Open up!" Dean Says As he bangs on the door as Sam opens the door to let in Dean and Mark both are still armed.

"Did you guys, uh, get to a phone?" Sam Asks

"Road block.I'm gonna have a word. Doc's inside." Dean Says

"What's going on out there, Dean?" Elena Asks

"I don't know, I feel like Chuck Heston in the Omega Man, I mean, Sarge is the only sane person I could find. What are we dealing with, do you know?" Dean Says

"Yeah. Doc thinks it's a virus." Sam Says

"Okay, great. What do you think?" Dean Says

"I think she's right." Sam Says

"Really?" Dean Asks

"Yeah. And I think the infected are trying to infect others with blood-to-blood contact. Oh, but it gets better. The uh, the virus? Leaves traces of sulfur in the blood." Sam Says

"A demonic virus?" Dean Asks

"Yeah, more like demonic germ warfare. At least it explains why I've been having visions." Elena Says

"It's like a Biblical plague." Dean Says

"Yeah. You don't know how right you are, Dean. I've been poring through Dad's journal, found something about the Roanoke colony." Sam Says

"And?" Dean Asks

"Dad always had a theory about Croatoan. He thought it was a demon's name. Sometimes known as Deva or sometimes Resheph. A demon of plague and pestilence." Sam Says

"Well, that, that's terrific. Why here, why now?" Dean Says

"I have no idea. But Dean, who knows how far this thing can spread? We gotta get out of here, we gotta warn people."Elena Asks

"They've got one! In here!" Mark Yells as they all renter the next room

"What do you mean?" Dean Asks

"The wife. She's infected." Sam Says

"We've gotta take care of this. We can't just leave her in there. My neighbors, they were strong. The longer we wait, the stronger she'll get." Mark Says As Dean barely hesitates before pulling out his gun and Walks into the lab.

__________________________________
THE LAB

"You're gonna kill Beverly Tanner?" Pam Says

"Doctor, could there be any treatment? Some kind of cure for this" Elena Asks

"Can you cure it?" Dean Asks

"For God's sake, I don't even know what "it" is!" Dr.Lee Says

"I told you, it's just a matter of time before she breaks through." Mark Says

"Just leave her in there, you can't shoot her like an animal!" Pam Says

"Sam." Dean Says As They go to the door of the utility room, where Beverly is being held. Dean and Mark hold their guns ready; Sam carefully opens the door, and Dean and Mark take up offensive positions. Inside, Beverly is huddled on the floor, knees drawn up. She jumps at their approach.

"Mark, what are you doing? Mark, it's, it's them! They locked me in here, they, they tried to kill me! They're infected, not me! Please, Mark! You've known me all your life! Please!" Beverly Says

"You sure she's one of 'em?" Dean Asks Sam and Elena nods, his face twisted in distress. As Mark pulls back, near tears, Dean steps forward and fires twice.

Later On in the Clinic, The shades are drawn, and Mark peers through them cautiously. A few people are gathered outside. Behind him, Sam pulls out a hunting knife and checks the blade as Dean and Elena loads guns. In the lab, Pam has just dropped a vial of blood; she screams.

"Oh god! Is there any on me? Am I okay?" Pam Asks

"You're clean, you're okay." Dr.Lee Says

"Why are we staying here? Please, let's just go!" Pam Says

"No, we can't, because those things are everywhere." Dean Says

"Oh god . . ." Pam Says

"Hey, shh, shh."Dr.Lee

"She's right about one thing. We can't stay here. We've gotta get out of here, get to the Roadhouse? Somewhere. Let people know what's coming." Sam Says

"Yeah, good point. Night of the Living Dead didn't exactly end pretty." Dean Says

"Well, I'm not sure we've got a choice. Lots of folks up here are good with rifles — even with all your hardware we're, we're easy targets. So unless you've got some explosives . . ." Mark Says as Sam glances up at a shelf of medical supplies and gets an idea."

"We could make some" Sam Says as he goes to the shelf and takes down a bottle of Potassium Chloride; just then, someone starts pounding frantically on the front door. They run out.

"Hey! Let me in, let me in! Please!" Duane Says

"It's Duane Tanner!" Mark Says As He opens the door and lets Duane in. He has a backpack and is limping.

"Thank god." Duane Says

"Duane, you okay?" Mark Asks

"That's the guy that I, uh, *clicks tongue*" Dean Says

"Yeah." Sam Says

"Who else is in here?" Duane Asks as Dean grabs his arm

"Hey, whoa, whoa, whoa, whoa, easy there, chief. Hey Doc! Give Duane a good once-over, would you?" Dean Says

"Pam?" Dr.Lee Says

"Who are you?" Duane Asks

"Never mind who I am. Doc." Dean Says

"Yeah, okay." Duane Says

"Duane. Where you been?" Mark Asks

"On a fishing trip up by Roslyn. I came back this afternoon. I . . . I saw Roger McGill being dragged out of his house by people we know! They started cutting him with knives! I ran, I've been hiding in the woods ever since. Has anybody seen my mom and dad?" Duane Says

He turns to Sam, attempting to joke, "Awkward . . ." Dean Says , Duane is sitting on a stool,his left leg has a deep gash in it.

"You're bleeding." Elena Says

"Where'd you get that?" Dean Asks

"I was running, I must have tripped." Duane Says

"Tie him up, there's rope in there." Dean Says

"Wait . . ." Duane Says

"Sit down!" Dean Says as he pulls his gun out on Duane

"I'm sorry, Duane, he's right. We've gotta be careful." Mark Says

"Careful? About what?" Duane Asks

"Did they bleed on you?" Dean Asks

"No, what the hell? No!" Duane Says

"Doc? Any way to know for sure, any test?" Sam Asks

"I've studied Beverly's bloodwork backwards and forwards." Dr.Lee Says

"My mom!" Duane Says

"It took three hours for the virus to incubate. The sulfur didn't appear in the blood until then, so . . . no, there'd be no way of knowing. Not until after Duane turns." Dr.Lee Says

"Dean, I gotta talk to you. Now. Elena Stay here okay" Sam Says as She Nods, Dean glances at Mark, who nods. Dean and Sam leave the lab.

"Sit in that chair." Mark Says

___________________________________
ANOTHER ROOM

"This is my vision, Dean. It's happening." Sam Says

"Yeah, I figured." Dean Says

"You can't kill him, all right? Not yet. We don't know if he's infected or not." Sam Says

"Well, I think we're pretty damn sure. Guy shows up out of nowhere, he's got a cut on his leg, his whole family's infected?" Dean Says

"All right, then we should keep him tied up, and we should wait and see." Sam Says

"For what? For him to Hulk out and infect somebody else? No thanks, can't take that chance." Dean Says As He starts to push past Sam, who stops him with a hand on his chest.

"Hey look, man, I'm not happy about this, okay? But it's a tough job and you know that." Sam Says

"Hey look, man, I'm not happy about this, okay? But it's a tough job and you know that." Dean Says

"It's supposed to be tough, Dean. We're supposed to struggle with this, that's the whole point." Sam Says

"What does that buy us?" Dean Asks

"A clear conscience, for one!" Sam Says

"Well, it's too late for that." Dean Says While Sam stops him again

"What the hell's happened to you?" Sam Asks

"What?" Dean Says

"You might kill an innocent man, and you don't even care! You don't act like yourself anymore, Dean. Hell, you know what? You're acting like one of those things out there." Sam Says

"Mm-hmm." Dean Says as he pushes past Sam a third time; Sam tries to stop him again but Dean hurls him against the far wall. He goes back into the hall and locks the door behind him.

"Hey!,Open the damn door, Dean! Don't do it, Dean! Don't!" Sam Says As Dean is now in the hallway from the vision in the Beginning. He drops the clip out of the gun and taps it against the butt, then replaces it. He opens the door to the lab and shuts it behind him;Duane is tied to the chair and Mark, Pam, Elena and Dr.Lee stand nearby.

"No, you're not gonna . . . No, no, I swear it's not in me!" Duane Says

"Oh God. We're all gonna die." Pam Says

"Maybe he's telling the truth." Mark Says

"Yeah Dean He could be telling the truth for all we know" Elena Says

"No, he's not him, not anymore." Dean Says

"Stop it! Ask her, ask the doctor! It's not in me!" Duane Says

"I . . . I can't tell." Dr.Lee Says

"Please, don't. Don't, please. I swear, it's not in me, it's not in me, I swear, I, I swear it's not in me. No, don't." Duane Says

"I got no choice." Dean Says as he points the gun towards Duane

"Yes you do look at me" Elena Says

"Move" Dean Says

"No Please don't do this your probably about to kill an innocent man okay please don't" Elena Says

"I'm gonna say this one last time Move" Dean Says

"Or What your gonna shoot me" Elena Says

"No Mark get her" Dean Says

"No Please don't do it" Elena Says as Mark moves her out the way

The moment stretches on Dean is pointing the gun at Duane with his finger hovering over the trigger, Duane is sobbing, the others watching in tense silence. Dean trembles, hesitates, and finally lowers the gun with a grimace.

"Damn it!" Dean Says As Duane pants in relief as Dean leaves the room.