The osler medical handbook -john hopkin
Section VIII – Infectious DiseasesSection Editors:Christopher Hoffmann, MD, MPH Nicola Zetola, MDChapter 53 – Fever of Unknown OriginScott Kim, MD Rachel Damico, MD, PhD Paul Auwaerter, MDFAST FACTS ▪ The contemporary understanding of fever of unknown origin (FUO) is derived from Petersdorf and Beeson's 1961 characterization of FUO. A stringent definition of FUO is composed of the following criteria[1]: temperature higher than 38.3° C measured on several occasions, 3-week duration (to exclude self-limiting fevers), negative blood cultures, no apparent explanation, and three outpatient visits or three hospital days. ▪ Infections, malignancies, and noninfectious inflammatory diseases account for the majority of cases of FUO. ▪ In patients older than 65 years, temporal arteritis should be considered early in any evaluation. ▪ Patients with FUO who remain undiagnosed after exhaustive study usually have a favorable prognosis. In one study, in a cohort of 61 patients with FUO discharged without diagnosis, the 5-year mortality rate was only 3.2%.[2]…

![[Harry Potter fanfic] Invincible Charm](https://truyen247.pro/images/harry-potter-fanfic-invincible-charm-373453053.webp)
![[BNHA X Đồng Nhân] THE POWER OF THE BLOCK WORLD](https://truyen247.pro/images/bnha-x-dong-nhan-the-power-of-the-block-world-306917239.webp)
![[BL-Truyện Thái] Cái Chết Của Singsala - Goddess Bless You From Death](https://truyen247.pro/images/bl-truyen-thai-cai-chet-cua-singsala-goddess-bless-you-from-death-407765163.webp)






![[NJW19.7Sins.3 | Written fic| Shortfic] Hoàng tử giả mạo và Quái vật mọt sách](https://truyen247.pro/images/njw19-7sins-3-written-fic-shortfic-hoang-tu-gia-mao-va-quai-vat-mot-sach-214077606.webp)


![[Trans][KookGa] I Think I Have A Thing For Maids](https://truyen247.pro/images/trans-kookga-i-think-i-have-a-thing-for-maids-73450221.webp)