The osler medical handbook -john hopkin
Section VIII – Infectious DiseasesSection Editors:Christopher Hoffmann, MD, MPH Nicola Zetola, MDChapter 53 – Fever of Unknown OriginScott Kim, MD Rachel Damico, MD, PhD Paul Auwaerter, MDFAST FACTS ▪ The contemporary understanding of fever of unknown origin (FUO) is derived from Petersdorf and Beeson's 1961 characterization of FUO. A stringent definition of FUO is composed of the following criteria[1]: temperature higher than 38.3° C measured on several occasions, 3-week duration (to exclude self-limiting fevers), negative blood cultures, no apparent explanation, and three outpatient visits or three hospital days. ▪ Infections, malignancies, and noninfectious inflammatory diseases account for the majority of cases of FUO. ▪ In patients older than 65 years, temporal arteritis should be considered early in any evaluation. ▪ Patients with FUO who remain undiagnosed after exhaustive study usually have a favorable prognosis. In one study, in a cohort of 61 patients with FUO discharged without diagnosis, the 5-year mortality rate was only 3.2%.[2]…


![[GL]LEVEL U](https://truyen247.pro/images/gl-level-u-47776010.webp)
![[Full] Hội trưởng đại ca, tiếp chiêu đi!](https://truyen247.pro/images/full-hoi-truong-dai-ca-tiep-chieu-di-97733091.webp)
![[HyungKyun|1shot|Written|T] Những Lừa Dối](https://truyen247.pro/images/hyungkyun-1shot-written-t-nhung-lua-doi-94506184.webp)





![[Trans] babyboy II Kookjin](https://truyen247.pro/images/trans-babyboy-ii-kookjin-151190075.webp)
