The osler medical handbook -john hopkin
Section VIII – Infectious DiseasesSection Editors:Christopher Hoffmann, MD, MPH Nicola Zetola, MDChapter 53 – Fever of Unknown OriginScott Kim, MD Rachel Damico, MD, PhD Paul Auwaerter, MDFAST FACTS ▪ The contemporary understanding of fever of unknown origin (FUO) is derived from Petersdorf and Beeson's 1961 characterization of FUO. A stringent definition of FUO is composed of the following criteria[1]: temperature higher than 38.3° C measured on several occasions, 3-week duration (to exclude self-limiting fevers), negative blood cultures, no apparent explanation, and three outpatient visits or three hospital days. ▪ Infections, malignancies, and noninfectious inflammatory diseases account for the majority of cases of FUO. ▪ In patients older than 65 years, temporal arteritis should be considered early in any evaluation. ▪ Patients with FUO who remain undiagnosed after exhaustive study usually have a favorable prognosis. In one study, in a cohort of 61 patients with FUO discharged without diagnosis, the 5-year mortality rate was only 3.2%.[2]…




![[hp+twilight] lord volturi](https://truyen247.pro/images/hp-twilight-lord-volturi-70737096.webp)


![[Thần Ma Đại Đế DN/AllTuyết] Học Viện Dã Lãng Cát](https://truyen247.pro/images/than-ma-dai-de-dn-alltuyet-hoc-vien-da-lang-cat-414756545.webp)









![[CHATROOM] Trồng Chúi Cùng Bác Thông](https://truyen247.pro/images/chatroom-trong-chui-cung-bac-thong-152994975.webp)

