This book talks about or hints at the following subjects:

Mental health illnesses

Addiction - drug and alcohol

Abuse - physical and mental/emotional

Sexual harassment

Talk between two characters about suicide (although no characters within this book attempt suicide)

Bullying

Child mortality

Sexual orientation

Reasons couples adopt, such as infertility and miscarriage

Mention of death and murder without explicit details

Please let me know if you read this list and have read this book, and I have left any important topics off of this list. Thanks.