Dame Maggie Smith as Headmistress Minerva McGonagall

Natalie Hallam as Deputy Heamistress and Astronomy Professor: Aurora Sinistra

Warrick Davis as Head of Ravenclaw and Charms Professor for Years 4-7: Professor Fillius Flitwick

Rosario Flores as Head of Gryffindor and Ancient Runes Professor: Professor Bathsheda Babbling

Jim Broadbent as Head of Slytherin and Potions Professor for Years 1-3: Professor Horace Slughorn

Miriam Margolyes as Head of Hufflepuff and Herbology Professor for Years 4-7: Professor Pomona Sprout

Sir Ian McKellen as Transfiguration Professor for Years 1-3: Professor Caleb Lyre

Billie Piper as Transfiguration Professor for Years 4-7: Professor Rosalind Jones

Öykü Karayel as Charms Professor for Years 1-3: Professor Rachel Nightingale

Alan Rickman as Potions Professor for Years 4-7: Professor Severus Snape

Ginnifer Goodwin as Herbology Professor for Years 1-3: Professor Juniper Anderson

Engin Öztürk as D.A.D.A Professor for Years 1-3: Professor Caden Evergreen

Giacomo Gianniotti as D.A.D.A Professor for Years 4-7: Professor Jordan Copper and

Brendan Gleeson as guest ex-Auror 'Mad-eye' Alastair Moody.

Robbie Coltrane as Care of Magical Creatures Professor for Years 3-5: Professor Rubeus Hagrid

Sonequa Martin-Green as Care of Magical Creatures Professor for Years 6-7: Professor Charlotte Threep