Peter Parker: Tom Holland

Felicia Hardy: Jayme Lynn Evans

Peter "Tobey" Parker: Tobey Maguire

Peter "Andrew" Parker: Andrew Garfield

Miles Morales: Alfred Enoch

Gwen Stacy: Emma Stone

Mary Jane "MJ" Watson

Otto Octavius

Adrian Toomes

Maxwell Dillon

Norman Osborn

Curt Connors