Ophelia HATES Starscream because first of all he's VERY annoying, delusional, and literally a nightmare but.... most all because he's the one that pushed she and Optimus to put their first sparkling (Smokescreen) in the care of Alpha Trion. The battle of Technar, led by Starscream was hours after she gave birth to Smokescreen, Optimus had no other choice but to fight and miss his own son's birth. Poor Ophelia lost her sister and her son on the same day thanks to a certain seeker. Starscream killed off Olympia who was Ophelia's last sibling after her brother died of Cybonic plague. Smokescreen was born on an Autobot ship stationed in Technar and fortunately Alpha Trion was there and gladly took Smokescreen with him to an escape pod and fled to save the little mech's life. Optimus and Ophelia both deeply hate the seeker for those long years of pain and guilt for missing out on so many years of their son's life, all because of Starscream's attack on their home city.