The more you know, the more confusing things get.

Simple.

Want examples? Keep reading.

Before advanced knowledge
After advanced knowledge

1) What created the universe?
I don't know/Nothing/God.
Well, we believe that there was such a thing as the Big Bang but the title doesn't quite fit because I'm actual fact we now believe it wasn't one big explosion but what was possibly billions and billions of explosions all over what might have been 2D space which led to the expansion of space into the 3D space we call the universe. But of course, we don't know for certain.

2) Who in the room would be the most dangerous to fight?
[A] because they're the strongest.
Well, that depends. [A] is the strongest but we all know they'd never hurt a soul whereas [B] looks like they would happily murder us, they just don't have money for a lawyer and [C] only lacks the strength. So I really couldn't tell you.

3) Name a healthy food.
Carrot.
Well, that depends what condition you have. If you have diabetes, sugar then becomes necessary for when you're low on it but most people would be better living without it. If you have a food obsession or addiction, it is mentally unhealthy to eat some foods that may otherwise be perfectly good. The list goes on so I'll just quickly mention that even with no medical condition at all, every food is healthy in moderation and every food is unhealthy in excess so it isn't really the food that is healthy or not but the amount of which you eat, and that then depends on your build and age. So I can't give you an answer.

Get what I mean now?

See, my original claim was absolutely simple. Wasn't it?
The more you know, the more confusing things get.

And then the more knowledge you had on it, with the examples, the less simple my claim began. Perhaps it made more sense, but it May have also confused you along the way.

So if someone asks you the question of whether or not more knowledge makes things simpler, how will you answer?
No.
Or, now that you've read this,
No, because you see.....