Running Up That Hill by Kate Bush is good (that "particular scene" from ST really hit HARD) but I like the Meg Myers cover WAY BETTER. 

I remember having Okami on the Switch (I still do) and I was sitting outside on my porch on a (summer?) evening, rapidly approaching the end of the game. (Yami is SO HARD TO DEFEAT, but I eventually did. He's even worse than Orochi.) My sibling's window was open, and they were cleaning their room. The Meg Myers cover was playing. 

God, that was an AMAZING feeling.