On many worlds, someone falls for Gwen Stacey... When it's Peter Parker, it's common for one night  to end in tragedy.  When she dies, Peter is forever marked mourning her and hating his mistake.  But in one world, he suffers a nervous breakdown when it happened. He didn't pull his punches when he fought the  Green Goblin killing  his Norman Osborn. Accidentally   shattering a vial of the Goblin serum  and inhaling, worsening his condition. Leaving him in a desperate vengeful sadistic state leading him to slaughter all of his foes. 

Becoming  what he hated, the new Goblin altering the attire in his damaged merciless state he combined his equipment with Norman's arsenal. 

 Having 'fun' as he  moved around the city slaughtering criminals and evading capture as the menace that knew the city better than anyone. Living like this till people from another dimensions were sent to his world. Then the   Spider-Woman Gwen Stacey  of Earth 65 came to save his life . Connecting with their tragedies, that Gwen  offered him a chance to make things right and invite him to join her and the other Spiders finally returning him to his right mind. Only for the attackers to stun her and lead him to sacrifice himself..

Dying with a smile on his face saying that he truly was saved.

" I'm good. But I can be better. Maybe I can't be the man you think I ought to have been but maybe I can be a better man than one I became when he died. "

Only to be revived by the Osborn serum in his veins, giving him another chance. The immortality of the OZ formula kicking in,  no longer harming his mind but augmenting his powers. In a world where he has plenty to explain and make up for. In a world where he's feared by everyone. Where he can't trust himself or his powers again... he'll get back up.