If you have Curie as a companion...
One day you and your group were traveling when Curie pats her coat pockets and looks through her bag frantically, she panicked and said that she needed to go to Vault 81 NOW, what do you do?

If you DONT have Curie as a companion...
You've caught wind of a vault called Vault 81, when you went to check it out and reach the door, some nearby speakers shout out, "Who are you?! What do you want?!" What do you do?