Haley Joel Osment voices as Danny Phantom/Fenton

Brandon Mychal Smith voices/Plays as Tucker Foley 

Willa Holland voices/Plays as Samantha "Sam" Manson

Alyson Stoner voices/plays as MariaBella (OC) 

Benjamin Diskin voices as Damian Masters aka Danny Phantom's Clone 1 (OC) 

Vincent Corraza Voices Zack Masters aka Danny Phantom's Clone 2 (OC)

Corey Burton voices as ClocksWorth 

Rob Paulson Voices as Jack Fenton, Technus 

Mark Hamill Voices as Danny's Half Ghost Mentor, Era (OC)

Lara Jill Miller Voices as Chipster, The Guardian between worlds (Life and Death) (OC)

Kelsey Lansdowne voices as Jazz Fenton

Robin Atkin Downes Voices as Vlad Masters

Travis Willingham Voices as Skulker

Will Friedle Voices as Dash

Vanessa Marshall voices as Maddie Fenton 

*Any Future Casts for other Characters will be written down when they appeared later on*