Okay, in this universe, everyone has been switched to the opposite gender! And they play a little bit if a different role in the game. Example-

Cuphead- Baroness Von Bon Bon
Mugman- Cala Maria

Others & Bosses

Laney Dice- Logan Dice
King Dice- Queen Dice
The Devil- Luci (fer)
Grim Matchstick- Gail Matchstick
Dr. Kahl- Dr. Kahlly
Sally Stageplay- Stuart Stageplay
Baroness Von Bon Bon- Candy Cuphead
Hilda Berg- Hector Berg
Rumor HoneyBottoms- Ronny HoneyBottoms
Cagney Carnation- Cally Carnation
Goopy Le Grande- Grace Le Grande
Djimi the Great- Dawn the Great
Beppi the Clown- Bella the Clown
Ribby and Croaks- Lilly and Hoppy
Cala Maria- MerMug (XD)
Wally Warbles- Wanda Warbles
Werner Werman- Wendy Werman
Captain Brineybeard- Captain Beth