Lily James as Jaqueline Cartier

Christy Altomare as Marguerite Cartier

Amanda Seyfried as Elizabeth Cartier

Elizabeth Olsen as Angelica Cartier

Derek Klena as James Wilder

Emmy Rossum as Evangeline Wilder

Ben Barnes as Sirius Black

Aaron Taylor Johnson as James Potter

Andrew Garfield as Remus Lupin

Karen Gillan as Lily Evans

Holland Roden as Lenora Scamander

Timothée Chalamet as Timothée Lafayette

Meryl Streep as Isobel Cartier

Matt Smith as Harry Bennett