Simone Ashley as Adhara Satrinava, formerly known as Pharaoh Queen Nefertari Setepenre of Upper and Lower Egypt

Johnathan Bailey as Elijah Mikaelson, the Possessive Original

Joseph Morgan as Niklaus Mikaelson, the Original Hybrid

Freddy Carter as Nikolai "Kol" Mikaelson, the Psychotic Mikaelson

Sarah Gadon as Freya Mikaelson, the Mikaelson Witch

Claire Holt as Rebekah Mikaelson, the Mikaelson Vampiress

Andrew Hozier as Finnick Mikaelson, the Noble Original

Jack Wolfe as Henrik Mikaelson, the Mikaelson Heretic

Amita Suman as Meketaten Setepenre, Crown Princess of Upper and Lower Egypt

Avantika Vandanapu as Ankhesenamun Setepenre, Princess of Upper and Lower Egypt

Blu Hunt as Inadu Labonair, Originator of the Labonair bloodline

Charles Michael Davis as Marcellus Gerard Mikaelson, Niklaus' Childe

Yusuf Gatewood as Vincent Griffith, descendant of Voodoo Queen, Marie Laveau

Phoebe Tonkin as Halia Andrea Labonair, descendant of Inadu

Kat Graham as Bonita "Bonnie" Bennett, descendant of Qetsiyah, Ayana and Marie Laveau

Gabriella Wilson as Belladonna "Donnie" Bennett, descendant of Qetsiyah, Ayana and Marie Laveau

Aaliyah Haughton as Qetsiyah, originator of the Bennett bloodline

Solange Knowles as Ayana Bennett, ancestor of Bonnie, descendant of Qetsiyah

Jaz Sinclair as Beatrice Bennett, descendant of Qetsiyah and Ayana

Bianca Lawson as Emily Bennett, descendant of Qetsiyah and Ayana

Jasmine Guy as Sheila Bennett, descendant of Qetsiyah and Ayana, Civil Rights Activist

Lisa Lopes as Abigail Bennett, descendant of Qetsiyah and Ayana, mother of Bonnie and Donnie

Tupac Shakur as Rudolphus Laveau, son of Marie Laveau, father of Bonnie and Donnie

Angela Bassett as Marie Laveau, Voodoo Queen of New Orleans

Emily Alyn Lind as Coraline Forbes, Indie Vampire

Nina Dobrev as Amara Petrova, Tatia Petrova, Katerina Petrova and Elena Gilbert, the Cursed Doppelgangers

Alfred Enoch as Matthew Donovan

Jensen Ackles as Alaric Saltzman

Paul Wesley as Silas and Stefan Salvatore

Ian Somerhalder as Damon Salvatore