Cau 30: cac hormon tuy thuong than: ban chat, tac dung, dieu hoa bai tiet va UDLS

*) Ban chat;

- cacm hormon tuy thg than dc tong hop tu L-tyrosin (la 1 a.a co mat trong thuc an)

- tren lsang: tap hop 3 chat dopamin, adrenalin va noradrenalin dc doi la catecholamin. Bthuong trong mau khoang 80% la adrenalin va 20% la noradrenalin.

*) Tac dung: adrenalin va noradrenalin trong mau khi dc dua den cac co quan dich chung gay ra tac dung hau nhu giong tac dung cua he TK giao cam. diem duy nhat khac do la thoi gian td tu 5 - 10 phut vi cac hormon nay thaI tru cham hon so voi cac hd cua he TK giao cam

- tac dung cau adrenalin:

+ tren co tim: lam tim dap nhanh, lam tang luc co bop cua co tim

+ tren mach mau: lam co mach duoi da, gi•m mach vanh, mach n•o, mach than va cac co van do do lam tang huyet ap toi da

+ tren cac co tron khac: lam gi•n co tron ruot non, tu cung, phe quan, bang quang, gi•n dong tu.

+ lam tang muc chuyen hoa cua toan bo co the: lam tang tieu thu oxy va tang sinh nhiet. chinh nho tac dung nay ma adrenalin lam tang hd va su hung phan cua co the.

+ lam tang phan giaI glycogen thanh glucose o gan va co do do tang giaI phong glucose vao mau

- tac dung cua noradrenalin:

Noradrenalin co td giong adrenalin nhung td tren mach mau thi manh hon, no lam tang ca HA toi da va ca HA toi thieu do lam co mach toan than. cac td len tim, len co tron db la td len chuyen hoa thi yeu hon adrenalin

*) Dieu hoa bai tiet;

Trong dk co so 2 hormon adrenalin va noradrenalin dc bai tiet it nhung trong tinh trang stress, lanh, dg huyet giam or khick thick he giao cam thi tuyen tuy thg than tang bai tiet ca 2 laoi hormon nay.

Nong do adrenalin trong mau o dk co so la 170 - 520pmol/l, con nong do noradrenalin la 0,3 - 28 nmol/l