ROAD

Dean is seen running on the road, hearing growling and barking noises behind him. He turns around a corner, runs into a shopping cart and falls to the ground. He sees a homeless man rummaging through a garbage bin.

"Run! It'll kill you!" Dean Says to the homeless man, then to a pink-ribboned Yorkie. Dean starts running while shouting at the same time.

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43 HOURS EARLIER

MORGUE

Coroner opens a body bag.

"Agent Tyler, Agent Perry, Agent Kramer meet Frank O'Brien." Coroner Says

"He died of a heart attack, right?" Sam Asks

"Three days ago." Coroner Says

"But O'Brien was 44 years old and, according to this ­ a marathon runner." Sam Says

"Everybody drops dead sooner or later. It's why I got job security." Coroner Says

"Yeah, but Frank kicked it here. Now, just yesterday, two perfectly healthy men bit it in Maumee. All heart attacks, you don't think that's strange?" Dean Asks

"Sounds like Maumee's problem to me. Why's the FBI give a damn, anyway?" Coroner Asks

"We just want to see the results of Frank's autopsy Sir" Elena Says

"What autopsy?" Corner Says

"The one you're gonna do." Elena Says Then Coroner cuts open the dead body.

"First dead body?" Coroner Says

"Far from it." Dean Says

"Oh, good. Because these suckers can get pretty ripe. Hey, hand me those rib cutters, would you?" Corner Asks Elena takes a fortifying breath while Dean picks up the cutters and hands it to the Coroner. Coroner cuts the ribs open

"Is that from a wedding ring? I didn't think Frank was married." Dean Says

"Ain't my department." Coroner Says

"Any idea how he got these?" Sam Says As he picks up Frank's arm which is full of scratches

"You know what? When you drop dead, you actually tend to drop. Body probably got scraped up when it hit the ground. Huh!" Coroner Says

"What?" Elena Says

"I-I can't find any blockages in any of the major arteries, Coroner breaks off the heart while Dean tries not to vomit, Heart looks pretty damn healthy. Hands heart to Dean, Hold that a second, would you? Sam and Elena smirks

Coroner cuts something else in the body, Then Blood Hits Sam and Elena in the face

"Oh, sorry. Spleen juice." Coroner Says As Dean Smirks at them

SHERIFF'S STATION

Sam, Elena and Dean sitting down in front of Deputy's desk, waiting. Deputy smiles at Dean. Sheriff opens his office door.

"Hell's bells, Linus, have you seen my.... Who are they?" The Sheriff Says As Elena, Sam and Dean stands

"Federal agents. I, uh...." Deputy Linus Says

"And you kept them waiting?" The Sheriff Says

"You, you said not to disturb." Deputy Linus Says

"Come on back Guys" The Sheriff Says As Sam & Dean and Elena walk over to Sheriff's office but Sheriff stops them, Uh Shoes off."

They take their shoes off and walk into Sheriff's office.

"Al Britton. Good to meet you." Sheriff Britton shakes Their Hands

"You too." Sam Says As Sheriff gestures for them to sit

"Thank you" Elena Says

Then the Sheriff takes out hand sanitizer and rubs his hands. Dean looks at Sam with a weird look on his face.

"Okay. So, what can I do for uncle Sam?" Sheriff Britton Says

"Well, we're looking into the death of Frank O'Brien. We understand some of your men found his body." Sam Says

"They did. Me and Frank, we were friends. Hell, we were gamecocks, Dean snickers and Sheriff gives him a stern look then Dean stops, That's our softball team's nameThey're majestic animals. I knew Frank since high school. To be honest, I just this morning got up the strength to go see him. Frank was...He was a good man." Sheriff Britton Says

"Yeah. Big heart." Dean Says

"Before he died, did you notice frank acting strange? Maybe scared of something?" Elena Asks

"Oh hell, yeah. Real jumpy" Sheriff Britton Says

"You know what scared him?" Elena Asks

"No. Wouldn't answer his phone. Finally, I sent some of my boys over to check on him, and well, you know the rest, He starts to pours more sanitizer on his hands again. Dean looks at Elena with a what "WTF?" look on his face, So, why the Feds give a crap? You don't really think there's a case here?" Sheriff Says

"No, no. It's probably nothing. Just a heart attack." Dean Says

OUTSIDE

"No way that was a heart attack" Dean Says

"Nope" Elena Says

"Definitely no way. Three victims, all with those same red scratches. All went from jittery to terrified to dead within 48 hours." Sam Says

"Something scared them to death?" Dean Says

"All right, so what can do that?" Elena Asks

"What can't? Ghosts, vampires, chupacabra? It could be a hundred things." Dean Says

"Yeah. So, we make a list and start crossing things off." Elena Says

"Alright, who's the last person to see Frank O'Brien alive?" Dean Asks

"Uh, his neighbour, Mark Hutchins" Sam Says As Dean Stops

"Hang on, hang on." Dean Says

"What?" Sam Says

"I don't like the looks of those teenagers down there. Sam and Elena looks around, sees teenagers talking near the Impala, Let's walk this way" Dean Says As He Crosses street while Sam and Elena stands looking at Dean confused

NEIGHBORS HOUSE

"Tyler, Perry and Kramer Just like Aerosmith." Mark Says As Dean is looking around the room.

"Yeah, small world. So, the last time you saw Frank O'Brien?" Sam Says As Dean sees a big lizard and suddenly faces forward

"Monday, he was watching me from his window. I waved at him, but he just closed the curtains." Mark Says

"Hmm. did you speak to him recently? Did he seem different? Uh, scared?" Sam Asks

"Oh, totally. He was freaking out." Mark Says As
Elena looks at Dean who looks freaked out too.

"Do you know, uh..do you know what scared him?" Dean Asks

"Well, yeah, witches." Mark Says

"Witches?" They All look at each other, Like...?" Sam Says

"Well, "Wizard of Oz" was on tv the other night, right? And he said that green bitch was totally out to get him." Mark Says

"Anything else scare him?" Elena Asks

"Everything else scared him. Al-Qaeda, ferrets, artificial sweetener. Those pez dispensers with their dead little eyes. Lots of stuff." Mark Says As Dean looks around again at the animals inside the aquariums

"So, tell me. What was Frank like?" Sam Asks

"I mean, he's dead, you know? I-I don't want to hammer him but, he got better." Mark Says

"He got better?" Sam Says

"Well, in high school he was, he was a dick." Mark Says

"A dick?" Elena Says

"Like a bully. I mean, he probably taped half the town's butt cheeks together, Dean chuckles, Mine included." Mark Says

"So he pissed a lot of people off. You think anyone would have wanted to get revenge?" Dean Says

"Well, I don't...Frank had a heart attack, right?" Mark Saya

"Just answer the question, sir." Sam Says

"No, I don't think so. Like I said, he got better. And after what happened to his wife." Mark Says

"His wife? So he was married." Dean Says

"She died about 20 years ago. Frank was really broken up about it, Dean starts staring at the snake around Mark's neck and he notices, Don't be scared of Donny. He's a sweetheart. It's Marie you got to look out for, She smells fear." Mark Says

An Albino snake creeps up from behind the couch, Elena Moves Slowly away from Dean Who sees it and gasps, he Stays very still while it crawls down his lap.

IMPALA

Dean and Elena are sitting in the car, Dean is reading while scratching on his left arm Elena looks over his shoulder, Sam opens passenger door and climbs in

"Hey. Any luck at the county clerk's office ?" Sam Asks

"I'm not sure I'd call it luck" Elena Says

"Frank's wife, Jessie, was a manic-depressive. She went off her meds back in '88 and vanished. They found her two weeks later, three towns over. Strung up in her motel room, suicide." Dean Says

"Any chance Frank helped her along to the other side?" Sam Asks

"No, Frank was working the swing shift when she disappeared. Airtight alibi." Dean Says As he Turns on car

They Are Driving in the middle of town.

"How was Frank's pad?" Elena Asks

"Clean. Searched it top to bottom. No EMF, no hex bags, no sulfur." Sam Says

"So probably no ghosts, no witches, no demons." Dean Says

"Pfh..." Elena Says

"3 down and 97 to go." Dean Says

"Yeah, Dude, you're going 20." Sam Says

"And?" Dean Says

"That's the speed limit." Sam Says

"What? Safety's a crime now?" Dean Says As he Drives through intersection, past their hotel.

"Dude, where are you going? That was our hotel." Elena Says

"Elena , I'm not gonna make a left-hand turn into oncoming traffic. I'm not suicidal." Dean Says
As Elena gives Dean a confused look.

"What?"Elena Says

"Did I just say that? That was kind of weird." Dean Says As the EMF goes off in the background.

"Do you hear something?" Sam Says As he Takes out EMF meter, moves it from and to Dean where it makes a sound

"Am I haunted? Am I haunted?!" Dean Says

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FRONT OF HOTEL

Sam is on the phone talking to Bobby, He Hears music from the Impala and walks towards it. Elena is Leaning Against The Door, He Sees Dean lying on the front seat doing air drums to Eye of the Tiger.

"It was the only thing that kept him calm" Elena Says Then Sam Bangs on the roof of the car and scares Dean.

"Dude. Look at this." Dean As he Shows scratches on arm

"I just talked to Bobby." Sam Says as he gives Dean A Box of Donuts

"And?" Dean Says As he Smells box of donuts and throws into car

"Um, well, you're not gonna like it." Sam Says

"What?" Dean Says

"It's ghost sickness." Sam Says

"Ghost sickness?" Dean & Elena Says

"Yeah." Sam Says

"God, no." Dean Says

"Yeah." Sam Says

"I don't even know what that is." Dean Says

"Okay. Some cultures believe that certain spirits can infect the living with a disease, which is why they stopped displaying bodies in houses and started taking them off to funeral homes." Sam Says

"Okay, get to the good stuff." Elena Says

"Symptoms are you get anxious..." Sam Says

"Yeah." Dean Says

"Then scared, then really scared, then your heart gives out. Sound familiar?" Sam Says

"Yeah, but Sam, we haven't seen a ghost in weeks." Dean Says

"Well, I doubt you caught it from a ghost. Look, once a spirit infects that first person, Ghost sickness can spread like any sickness through a cough, a handshake, whatever. It's like the flu. Now, Frank O'Brien was the first to die, which means he was probably the first infected. Patient zero." Sam Says

"Our very own outbreak monkey." Dean Says

"Right. Get this, Frank was in Maumee over the weekend. Softball tournament. Which is where he must have infected the other two victims." Sam Says

"Were they gamecocks?" Elena Asks

"Cornjerkers." Sam Says

"So, ghosts infected Frank. He passed it on to the other guys and I got it from his corpse?" Dean Says

"Right." Sam Says

"So now what, I have 48 hours before I go insane and my heart stops?" Dean Asks

"More like 24." Sam Says

"Super." Dean Says

"Here we go again" Elena Says

"Yeah." Sam Says

Well, why me? Why not you or Lena? I mean, you two got hit with the spleen juice." Dean Says

"Yeah, um, you see Bobby and I have a theory about that too. Turns out all three victims shared a certain, uh, personality type. Frank was a bully. The other two victims, one was a vice principal, the other was a bouncer." Sam Says

"Okay." Dean Says

"Basically, they were all dicks." Sam Says

"Huh" Elena Says

"Huh What?, So you're saying I'm a dick?" Dean Says

"No, no, no." Elena & Sam Says

"It's not just that. All three victims used fear as a weapon, and now this disease is just returning the favor." Sam Says

"I don't scare people." Dean Says

"Dean, all we do is scare people." Elena Says

"Okay, well then, you're a dick too." Dean Says

"Apparently, I'm not." Elena Says

"Whatever. How do we stop it?" Dean Asks

"We gank the ghost that started all this. We do that, the disease should clear up." Sam Says

"You thinking Frank's wife?" Dean Says

"Who knows why she killed herself, you know? Hey, what are you two doing waiting out here, anyway?" Sam Asks

"Our room's on the fourth floor, Sam looks and shakes head While Elena rolls her eyes, It's...it's high." Dean Says

"I'll see if I can move us down to the first." Sam Says

"Thanks." Dean Says

"Sure." Sam Says Then Dean climbs into the Impala and looks at donuts.

HOTEL ROOM

Dean sits at table with book in front of him. Stares at wall clock ticking loudly in the background. Goes back to reading and starts coughing when he sees disturbing images. Sees words that seem to be talking to him and starts to panic, Irritatingly looks back at the clock then there is a sound of something breaking.

Sam and Elena comes into room, sees broken clock on floor. Dean is on the sofa drinking beer.

"Hey There" Elena Says

"Everything all right?" Sam Asks

"Oh,yeah. Just peachy. Find anything?" Dean Asks

"Yeah, Jessie O'Brien's body was cremated, so I'm pretty sure she is not our ghost." Sam Says

"Hey, quit picking at that. How you feeling?" Elena Asks

"Awesome. It's nice to have my head on the chopping block again. I almost forgot what that feels like." Dean Says

"Yeah." Sam Says

"It's freaking delightful." Dean Says

"We'll keep looking, Dean starts to cough, You okay?" Sam Asks

"Hey!, Dean! Dean!" Elena Says As Dean starts to choke.

"Dean." Sam Says As Dean Starts gagging over the sink where he spits out a wood chip.

"We've been completely ignoring the biggest clue we have, you." Sam Says

"I don't want to be a clue." Dean Says

"The abrasions, this, the disease, it's trying to tell us something." Elena Says

"Tell us what, wood chips?" Dean Asks

"Exactly." Sam Says

OUTSIDE THE LUMBER MILL

Dean looks at the mill apprehensively.

"I'm not going in there." Dean Says

"I need backup, you and Elena is all I've got. You're going in, Dean." Sam Says

"Come On Dean You got this" Elena Says As She pats his back, Then Dean Takes a drink of whiskey

"Let's do this. It is a little spooky, isn't it?" Dean Says Then Sam hands Dean a gun.

"Oh, I'm not carrying that. It could go off. I'll man the flashlight." Dean Says

"You do that." Sam Says

INSIDE THE LUMBER MILL

EMF goes off in the background.

"EMF's not gonna work with me around, is it?" Dean Asks

"You don't say. Come on." Sam Says

"Wait...Dean Gets Startled. To Frank. Love, Jessie." Frank O'Brien's ring." Elena Says

"What the hell was Frank doing here?" Dean Asks

"No idea." Sam Says

They Walks into a room full of lockers where they hear rustling.

"One Three, One..Two.. Three" Sam Says As he opens a locker and Dean screams after being startled by a cat While Elena and Sam Looks At Him

"That was scary!, Sam and Elena walks away, Wait." Dean Says, In the next room sam finds an ID

"Luther Garland." Sam Says As Dean Sees a drawing

"Hey, this is uh...this is Frank's wife." Dean Says

"Plot thickens." Elena Says

"Yeah, but into what?" Dean Says As he tears off the drawing and machines turn on. Looking around he sees something in the corner. Sam and Elena looks at Dean and sees him looking behind them, They turns around and sees the same thing.

"Hey!" Sam Says As he Turns around and sees Dean running out the mill

"Unbelievable" Elena Says As She and Sam shoots the Ghost and goes after Dean who is hiding behind the Impala taking another drink.

"Guess we got the right place." Sam Says

"Ya Think" Elena Says